The power drop between match 1 and match 2, as well as between match 1 and match 3, were also similar in the 3 trials. Plasma glucose and insulin concentrations in the 3 trials were shown in Figures 2 and 3, respectively.
After supplementations at the end of match 2, the CHO and CHO+AA trial showed significantly higher glucose TGF-beta inhibitor concentration at 30 min, and significantly higher insulin concentration after 30, 60, and 90 min. MK-4827 Compared to the placebo trial, the CHO and CHO+AA trial also showed significantly higher AUC in glucose (Placebo: 428.69 ± 24.80; CHO: 621.85 ± 41.28; CHO+AA: 550.66 ± 32.89 arbitrary unit; p < 0.01) and insulin concentrations (Placebo: CUDC-907 chemical structure 368.99 ± 68.24; CHO: 2947.01 ± 665.08; CHO+AA: 2896.27 ± 557.40 arbitrary unit; p < 0.01) during the 2-hr recovery period after match 2. However, there was no significant difference between the CHO and CHO+AA trial in either glucose or insulin concentration at any time point. The AUC of plasma glucose and insulin concentrations were also similar between the CHO and CHO+AA trials. Table 1 Peak and average power in 3 matches in the 3
trials1 Placebo trial CHO trial CHO+AA trial Peak power 1st match (W/kg) 70.36 ± 3.38 71.24 ± 4.19 72.62 ± 4.59 2nd match (W/kg) 69.45 ± 5.40 69.05 ± 5.42 72.08 ± 6.14 3rd match (W/kg) 67.49 ± 4.81 68.72 ± 4.84 new 72.52 ± 8.18 Average power 1st match (W/kg) 61.97 ± 3.33 63.90 ± 3.82 64.24 ± 4.14 2nd match (W/kg) 61.41 ± 4.84 61.05 ± 4.59 63.48 ± 5.54 3rd match (W/kg) 59.27 ± 4.15 60.89 ± 4.42 63.85 ± 7.09 Drop in peak power Match 1 – Match 2 (%) 1.93 ± 5.07 3.35 ± 4.36 1.49
± 4.14 Match 1 – Match 3 (%) 4.62 ± 3.93 3.52 ± 3.75 2.17 ± 6.61 Drop in average power Match 1 – Match 2 (%) 1.28 ± 5.18 4.58 ± 4.23 2.00 ± 4.14 Match 1 – Match 3 (%) 4.54 ± 4.10 4.65 ± 4.04 2.59 ± 6.45 1 Each trial contained 3 matches with a 1-hr rest between match 1 and 2 and a 2-hr rest between match 2 and 3. A match contained 3 exercise periods lasting 2 minutes each with a work to rest ratio of 10 seconds: 20 seconds. After each exercise period, a 2 minute rest period was provided before the next exercise period. The load was 0.1 kp/kg body weight. All values are means ± SEMs. Data were analyzed by using repeated measures ANOVA with time and group as factors. No significant main effect was observed for any of the variables. Figure 2 Plasma glucose concentrations in the 3 trials. Data were analyzed by using repeated measures ANOVA with time and group as factors. Treatment effect p = 0.006; time effect p < 0.001; interaction effect p < 0.001. *CHO trial significantly different from placebo trial at the same time point (p < 0.05).