, 2003) Data Analysis We first evaluated participant-rated accep

, 2003). Data Analysis We first evaluated participant-rated acceptability of Dovitinib msds the CD-5As program using descriptive analysis. Second, we evaluated changes in self-reported motivation, self-efficacy, and intention to change among participants receiving the CD-5As program using paired samples t tests. Third, we examined the proportion of participants assigned to CM-Lite who actively participated in the incentive program, as well as the frequency of success and subjective responses to CM-Lite among those who did participate. Fourth, following evaluation of the success of randomization, we examined differences in abstinence between experimental conditions (CD-5As, CM-Lite, and combined) and the control condition using logistic regression with the categorical covariates procedure.

All analyses were on an intent -to-treat basis that analyzed participants as allocated to condition without respect to completion of treatment elements. These analyses controlled for level of smoking at baseline as well as any variables found to differ between groups at p �� .10 (with unadjusted analyses also presented). Secondary analyses of intervention effects on help-seeking and sustained abstinence were also conducted. Finally, we collapsed across conditions in order to compare participants receiving CD-5As (with or without CM-Lite) with those who did not. These collapsed groups are hereafter referred to as ��intervention groups�� in order to distinguish them from conditions defined above.

Results A total of 1,317 participants were screened between July of 2008 and November of 2009; 1,207 were excluded, primarily due to being beyond 27-week gestation or denying smoking in the past week (Figure 1). The trial ended after 110 participants were randomized. These 110 randomized participants (26 in CD-5As, 28 in CM-Lite, 30 in the combined condition, and 26 in TAU) averaged 27.9 (SD = 6.4) years of age, with a range of 18�C44; a total of 90 (81.8%) were Black, with one participant reporting Hispanic ethnicity. Cigarettes per day in the week prior to recruitment averaged 8.0 (SD = 8.2, range = 1�C50). A total of 57 participants (52.8%) scored above the FTND cutoff for nicotine dependence. See Table 1 for details on baseline participant characteristics and differences between conditions on those variables. There were no significant differences between conditions on any of the baseline characteristics examined, although one variable (minority vs.

nonminority race) was below p = .10 and so was controlled for in subsequent analyses. There were no site differences on any baseline or demographic variables, so subsequent analyses collapsed across site. Table 1. Sample Characteristics Carfilzomib at Baseline by Condition (N = 110) Figure 1. Participant flow. Follow-up evaluation took place between January of 2009 and January of 2010 at a mean of 10.1 (SD = 3.9) weeks postrandomization/intervention; a total of 94 (85.

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