30–1.34(t,3H,CH3), δ 4.24–4.33(q,2H,CH2), δ 5.35(s,2H,NH2), δ 6.22(s,1H,CH), δ 5.2 (s,1H,OH), δ 7.62–7.51(m,3H,Ar H), δ 7.90(m,4H,Ar H). EI-MS: (m/z:RA): 399(M+ 71%); 397(M+2 48%); % Anal.: calculated: C 56.79%,H 4.01%, N 10.46%,O 11.94%, Found: C 56.84%,H 4.06%.N 10.38%,O 11.68%. FT–IR (KBr): 3440(N–H str), 3095(C–H str), 1720(C O str), 1590(C N str), Raf inhibitor 1529(–NO2str), 1272(C–S str), 1H NMR (DMSO-d6) δ ppm:, δ 1.31–1.32(t,3H,CH3), δ 4.24–4.33(q,2H,CH2), δ 5.35(s,2H,NH2), δ 6.26(s,1H,CH), δ 6.82–7.41(m,3H,Ar H), δ 7.9(m,4H,Ar H). EI-MS: (m/z:RA): 440(M+ 62%). Anal.: calculated: C 51.70%, H 3.43%,N

15.87%, O 21.75.Found:C 51.76%,H 3.26%. N 15.54%, O 21.68%. FT–IR (KBr): 3385(N–H str), 2943(C–H str), 1722(C O str), 1635(C N str), 1519(C C str), 1288(C–S

str), 1H NMR (DMSO-d6) δ ppm:, δ 1.34–1.36(t,3H,CH3), δ 4.22–4.31(q,2H,CH2), δ 5.13(s,2H,NH2), δ 6.62–7.11(m,3H,Ar H), δ 6.30(s,1H,CH), δ 7.42(m,2H,Ar H), δ 8.2(s,9H). EI–MS: (m/z:RA): 484(M+ 62%); % Anal.: calculated: C 54.31%,H 4.56%, N 11.52%, O 23.02%.Found: C 54.42%, H 4.47%,N 11.23%,O 23.00%. FT-IR (KBr): 3424(N–H str), 3022(C–H str), 1720(C O str), 1630(C Nstr), 1520(C C str), 1264(C–S str), 750(C–Cl str), 1H NMR (DMSO-d6) δ ppm:, δ 1.34–1.37(t,3H,CH3), δ BMS-777607 supplier 3.82–4.36(q,2H,CH2), δ 5.23(s,2H, NH2), δ 8.32(s,9H), δ 6.23(s,1H,CH), δ 6.62–7.11(m,3H,Ar H), δ 7.42(m,2H,Ar H). EI-MS: (m/z:RA): 474(M+

74%),472(M+2 25%); % Anal. :calculated :C 55.52%, H 4.66%, N 8.83%,O 16.81. Found: C 55.64%, H 4.56%, N 8.65%, O 16.67%. FT–IR (KBr): 3414(N–H str), 2979(C–H str), 1729(C O str), 1602(C N str), 1530(C Cstr), 1265(C–S str). 1H NMR(DMSO-d6) δ ppm:, δ 1.32–1.38(t,3H,CH3), δ 3.72–4.35(q,2H,CH2), δ 5.43(s,2H, NH2), δ 6.04(S,1H,CH), δ 6.64–7.08(m,3H,Ar H), δ 7.22(m,2H,Ar H). EI-MS: (m/z: RA): 470(M+ 68%); % Anal.: calculated: C 58.59%, H Montelukast Sodium 5.34%, N 8.91%, O 20.36%.Found: C 58.87%, H 5.31%, N 8.74%, O 20.14%.