57 of these were prior to installation of OCI and 65 after instal

57 of these were prior to installation of OCI and 65 after installation. Median DAP was significantly lower after installation of OCI (4.9 mGy m(2); range 1.25-13.3) than it had been before installation (6.9 mGy m(2); range 1.91-95.0) (p = 0.005). Median screening times before and after installation of

OCI were 20.0 min and 16.2 min respectively this website (p = 0.027) and median contrast volumes before and after the change to OCI were 100 ml and 90 ml respectively (p = 0.21).

Conclusion: Introduction of operator-controlled imaging can significantly reduce radiation exposure during EVAR, with particular reduction in the number of ‘higher-dose’ cases. (C) 2012 European Society for Vascular Surgery. Published by Elsevier Ltd. All rights reserved.”
“Purpose of review

Bone regeneration and fracture repair are the complex processes of mesenchymal stem cell invasion, chondrogenesis, osteogenesis and angiogenesis. The coordinated actions of these principal

processes result in the reconstruction of a normal bone and restoration of a structural unit. However, these normal bone regenerative mechanisms breakdown during fracture repair failure and postmenopausal osteoporosis.

Recent findings

Recent discoveries of circulating multipotent stem cells with mixed characteristics of endothelial cell and osteogenic capacity have raised interest in new and potentially breakthrough therapies for fracture and pathologic FDA-approved Drug Library cost bone loss. The cooperative actions of other mesenchymal stem cell lineage such as adipocytes and processes such as angiogenesis in bone repair could also serve as novel therapeutic targets. Recent data suggest that anabolic parathyroid hormone therapy, already approved for the treatment of osteoporosis,

may recruit osteoprogenitor cells and also have a role in fracture repair.


The present review will highlight recent information on stem cells and bone repair and examine potential avenues for future research.”
“Objectives: The aim of this study is to present novel ex-vivo models in the study of complex haemodynamical changes in Stanford type B aortic dissection (TBAD).

Materials and methods: Fifteen fresh porcine aortas were harvested and preserved Belnacasan manufacturer with 4 C saline. Ex-vivo models were developed to simulate TBAD in three different situations: model A with patent false lumen, model B with distal re-entry only and model C with proximal primary entry only. These models were connected to standardised pulsatile pumps and the pressure waveforms were monitored and compared. The aortas were scanned with ultrasonography and subjected to post-experiment autopsy.

Results: The three different models were successfully created (n = 13). Pulsatile flow testing was successful and the shapes of the pressure waveforms were similar to those taken from human aorta. Post-testing gross examination confirmed the success of modelling.

Conclusion: Porcine aortas may prove to be useful ex-vivo models in the study of aortic dissection haemodynamics.

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